Download Knockout And Transgenic Mice Images. Knockout mice = removal/masking/inhibiting of specific endogenous gene, due to this mice does not express particular that gene. Transgenic and knockout technology have been particularly useful in the kidney as various transgenic mouse models have been successfully generated to gain a better understanding of renal physiology at the gene level.
• transgenesis refers to the phenomenon of introduction of exogenous dna into the genome to create and maintain a stable heritable character.
Behavioral phenotyping of transgenic and knockout mice. A knockout mouse is a laboratory mouse in which researchers have inactivated, or knocked out, an existing gene by replacing it or knocking out the activity of a gene provides valuable clues about what that gene normally does. This retinal degeneration is comparable to human retinitis pigmentosa. How they make them and why.